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Review Article Open Access


Herbal Antibacterials: A Review

Chirag Modi, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, Madhavi Awale.

Cited by (3)

Abstract
Plants are rich source of antibacterial agents because they produce wide array of bioactive molecules, most of which probably evolved as chemical defense against predation or infection. A major part of the total population in developing countries still uses traditional folk medicine obtained from plant resources With an estimation of WHO that as many as 80% of world population living in rural areas rely on herbal traditional medicines as their primary health care, the study on properties and uses of medicinal plants are getting growing interests. In recent years this interest to evaluate plants possessing antibacterial activity for various diseases is growing. Different solvent extracts (aqueous, alcohol and ethanol) of leaves, flower and seed of various plants selected based on an ethnobotanical survey from India were subjected to in vitro antibacterial activity assay against Gram-positive and Gram-negative bacteria employing different diffusion method. Based on local use of common diseases and Ethnobotanical knowledge, an attempt has been made to assess the antibacterial properties of selected medicinal plants viz. Argemone mexicana (Shialkanta), Aster lanceolatus (White panicle), Capparis thonningii and Capparis tomentosa (Woolly caper bush), Cardiospermum halicacabum (Balloonvine), Cassia alata (Herpetic alata), Centaurea sclerolepis, Cinnamomum zeylanicum (Cinnamon), Curcuma longa (Turmeric), Cymbopogon nervatus, Ficus religiosa (Peepal), Indigofera aspalathoides (Ajara), Marrubium vulgare (Horehound), Medicago Spp.(Medick, Burclover), Morus alba (Mulberry), Ocimum sanctum (Tulsi), Origanum marjorana (Marjoram), Oxalis corniculata (Amli), Piper nigrum (Kala mirch), Plectranthus amboinicus (Indian borage, Patharchur), Plumeria acutifolia (Kachuchi), Salvadora persica (Piludi), Salvia repens and Syzygium aromaticum (Clove) for potential antibacterial activity against some important bacterial strains, namely Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas spp, Proteus spp, Salmonella Typhi, Escherichia coli, Shigella dysentriae, Klebsiella pneumoniae. The plant extracts were more active against Gram-positive bacteria than against Gram-negative bacteria.

Key words: Antibacterial plants, herbs, plant extract


 
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REFERENCES
1. Fransworth NR. 1994. The role of medicinal plants in drug development. In: Krogsgaard Larsen, S., Brogger-Christense, S., Kofod, H. (Eds.), Natural Products and Drug Development, Munksgaard, Copenhagen.
2. Clark AM, Hufford CD. Discovery and development of novel prototype antibiotics for opportunistic infections related to acquired immunodeficiency syndrome. Kinghorn AD, Balandrin MF, Editors, Human Medicinal Agents from Plants. ACS Symposium Series 534, American Chemical Society, Washington, USA; 1993. pp. 228-240.
3. Dubey NK, Kumar R, Tripathi P. Global promotion of herbal medicines: India's opportunity. Curr Sci. 2004; 86: 37-41.
4. Karaman L, Sahin F, Gulluce M, Ogutcu H, Sngul M, Adiguzel A. Antimicrobial activity of aqueous and methanol extracts of Juniperusoxycedrus L. J Ethnopharmacol. 2003; 85: 231-235. [DOI via Crossref]   
5. Schinor EC, Salvador MJ, Ito IY, Dias DA.Evaluation of the antimicrobial activity of crude extracts and isolated constituents from Chrestascapigera.Brazilian J MIcrobiol.2007; 38: 145-149. [DOI via Crossref]   
6. Essawi T, Srour M. Screening of some Palestinian medicinal plants for antibacterial activity. J Ethanopharmacol.2000; 46: 343-349. [DOI via Crossref]   
7. Iwu MW, Duncan AR, Okunji CO. New antimicrobials of plant origin, In: Janick J, eds., Perspectives on New Crops and New Uses. Alexandria, VA, ASHS Press: 1999. pp. 457-462.
8. Bhattacharjee I, Chatterjee SK, Chatterjee S, Chandra G. Antibacterial potentiality of Argemonemexicana solvent extracts against some pathogenic bacteria. MemInstOswaldo Cruz. 2006; 101(6): 645-648. [DOI via Crossref]    [Pubmed]   
9. Dias JFG, Virtuoso S, Davet A, Cunico MM, Miguel MD, Miguel OG, et al. Antibacterial and antifungal activity of ethanolics extracts from Aster lanceolatusWilld.,Asteraceae. Brazilian Journal of Pharmacognosy. 2006; 16(1): 83-87.
10. Sama W, Ajaiyeoba EO. Phytochemical and antimicrobial studies of Capparisthonningii and Capparistomemtosa.Pharmacognosy Magazine. 2006; 2(6): 119-121.
11. Girish HV, Sudarshana MS, Rati RE. In vitro evaluation of the efficacy of leaf and its callus extracts of Cardiospermumhalicacabum L. on important human pathogenic bacteria. Advances in Biological Research. 2008; 2(1-2): 34-38.
12. Ismail EN, Somchit MN, Abdul RM.In vitro antibacterial activity and effect of Cassia alata in livers of mice.Proceedings of the Regional Symposium on Environment and Natural Resources.2002; 1: 509-515.
13. Arslanyolu M, Erdemgil FZ. Evaluation of the antibacterial activity and toxicity of isolated arctiin from the seeds of Centaureasclerolepis. J Fac Pharm. 2006; 35(2): 103-109.
14. Gende LB, Floris I, Fritz R, Eguaras MJ. Antimicrobial activity of cinnamon (Cinnamomumzeylanicum) essential oil and its main components against Paenibacillus larvae from Argentine.Bulletin of Insectology. 2008; 61(1): 1-4.
15. Singh R, Chandra R, Bose M, Luthra PM. Antibacterial activity of Curcuma longa rhizome extract on pathogenic bacteria. Current Science. 2002; 83(6): 737-740.
16. El-Kamali HH, Hamza MA, El-Amir MY. Antibacterial activity of the essential oil from Cymbopogonnervatus inflorescence.Fitoterapia. 2005; 76(5): 446-449. [DOI via Crossref]    [Pubmed]   
17. Uma B, Prabhakar K, Rajendran S. In vitro antimicrobial activity and phytochemical analysis of Ficusreligiosa L. and Ficusbengalensis L. against DiarrhoealEnterotoxigenic E. Coli.Ethnobotanical Leaflets.2009; 13: 472-74.
18. Rajkapoor B, Murugesh N, Kavimani S, Krishna DR, Ravichandran V, Gobinath M, et al. Antimycobacterial, antiviral and cytotoxic studies of IndigoferaaspalathoidesVahl. Pharmacognosy Magazine. 2007; 3(11): 163-166.
19. Masoodi MH, Ahmed B, Zargar IM, Khan SA, Khan S, Singh P. Antibacterial activity of whole plant extract of Marrubiumvulgare. African Journal of Biotechnology. 2008; 7(2): 86-87.
20. Avato P, Bucci R, Tava A, Vitali C, Rosato A, Bialy Z, et al. Antimicrobial activity of saponins from Medicago sp.: structure-activity relationship. Phytotherapy Research. 2006; 20(6): 454-457. [DOI via Crossref]    [Pubmed]   
21. Park KM, You JS, Lee HY, Baek NI, Hwang JK. Kuwanon G: an antibacterial agent from the root bark of Morusalba against oral pathogens. Journal of Ethnopharmacology. 2003; 84(2-3): 181-185. [DOI via Crossref]   
22. Joshi B, Lekhak S, Sharma A. Antibacterial property of different medicinal plants: Ocimum sanctum, Cinnamomumzeylanicum, Xanthoxylumarmatum and Origanummarjorana. Kathmandu university journal of science, engineering and technology. 2009; 5(1): 143-150.
23. Leeja L, Thoppil JE. Antimicrobial activity of methanol extract of Origanummarjorana L. (Sweet marjoram).Journal of Environmental Biology. 2007; 28(1): 145-146. [Pubmed]   
24. Satish S, Raghavendra MP, Raveesha KA. Evaluation of the antibacterial potential of some plants against human pathogenic bacteria.Advances in Biological Research. 2008; 2(3-4): 44-48.
25. Patil MK, et al. Antibacterial efficacy of Piper nigrum fruit. Journal of Veterinary Pharmacology and Toxicology. 2007; 2(1-2): 69-71.
26. Kumar VS, Ahmed SM, Badami S, Anil TM and David B. Antibacterial activity of aqueous extract of Coleus amboinicus. Pharmacology online.2008; 3: 224-226.
27. Rasool SN, Jaheerunnisa S, Chitta SK, Jayaveera KN. Antimicrobial activities of Plumeriaacutifolia. Journal of Medicinal Plants Research. 2008; 2(4): 77-80.
28. Al-Bayati FA, Sulaiman KD. In vitro Antimicrobial activity of Salvadorapersica L. extracts against some isolated oral pathogens in Iraq. Turk J Biol. 2000; 32: 57-62.
29. Mayekiso B, Magwa ML, Coopoosamy RM. The chemical composition and antibacterial activity of the leaf extract of Salvia repens Burch. Ex Benth.Journal of Medicinal Plants Research. 2008; 2(7): 159-162.
30. Pandey A, Singh P. Antibacterial activity of Syzygiumaromaticum (clove) with metal ion effect against food-borne pathogens. Asian Journal of Plant Science and Research. 2011; 1(2): 69-80.
31. Tona L, Kambu K, Ngimbi N, Cimanga K, Vlietinck AJ. Antiamoebic and phytochemical screening of some Congolese medicinal plants.J Ethnopharmacol.1998; 61: 57-65. [DOI via Crossref]   
32. Tadeg H, Mohammed E, Asres K, Gebre-Mariam T. Antibacterial activities of some selected traditional Ethiopian medicinal plants used in the treatment of skin disorders. J Ethnopharmacol.2005; 100: 168-175. [DOI via Crossref]    [Pubmed]   

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How to Cite this Article
Pubmed Style

Modi C, Mody S, Patel H, Dudhatra G, Kumar A, Awale M. Herbal Antibacterials: A Review. J Intercult Ethnopharmacol. 2012; 1(1): 52-61. doi:10.5455/jice.20120207113423



Web Style

Modi C, Mody S, Patel H, Dudhatra G, Kumar A, Awale M. Herbal Antibacterials: A Review. www.scopemed.org/?mno=14693 [Access: November 18, 2017]. doi:10.5455/jice.20120207113423



AMA (American Medical Association) Style

Modi C, Mody S, Patel H, Dudhatra G, Kumar A, Awale M. Herbal Antibacterials: A Review. J Intercult Ethnopharmacol. 2012; 1(1): 52-61. doi:10.5455/jice.20120207113423



Vancouver/ICMJE Style

Modi C, Mody S, Patel H, Dudhatra G, Kumar A, Awale M. Herbal Antibacterials: A Review. J Intercult Ethnopharmacol. (2012), [cited November 18, 2017]; 1(1): 52-61. doi:10.5455/jice.20120207113423



Harvard Style

Modi, C., Mody, S., Patel, H., Dudhatra, G., Kumar, A. & Awale, M. (2012) Herbal Antibacterials: A Review. J Intercult Ethnopharmacol, 1 (1), 52-61. doi:10.5455/jice.20120207113423



Turabian Style

Modi, Chirag, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, and Madhavi Awale. 2012. Herbal Antibacterials: A Review. Journal of Intercultural Ethnopharmacology, 1 (1), 52-61. doi:10.5455/jice.20120207113423



Chicago Style

Modi, Chirag, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, and Madhavi Awale. "Herbal Antibacterials: A Review." Journal of Intercultural Ethnopharmacology 1 (2012), 52-61. doi:10.5455/jice.20120207113423



MLA (The Modern Language Association) Style

Modi, Chirag, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, and Madhavi Awale. "Herbal Antibacterials: A Review." Journal of Intercultural Ethnopharmacology 1.1 (2012), 52-61. Print. doi:10.5455/jice.20120207113423



APA (American Psychological Association) Style

Modi, C., Mody, S., Patel, H., Dudhatra, G., Kumar, A. & Awale, M. (2012) Herbal Antibacterials: A Review. Journal of Intercultural Ethnopharmacology, 1 (1), 52-61. doi:10.5455/jice.20120207113423





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