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Original Research Open Access


Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits

Kanwal Zahra, Muhammad Imran Sohail, Muhammad Anwar Malik.

Abstract
Aim: Liver function tests, including total plasma proteins, albumin, bilirubin and glucose were analyzed to find out the hepatocurative and hepatoprotective effects of Momordica charantia.
Method: The study was divided into two categories. In first category, the livers of rabbits were intoxicated with acetaminophen, and then Momordica fruit extract was given to observe its hepatocurative effects.
Results: The results indicated significant changes in concentrations of the parameters in acetaminophen-challenged rabbits. In the second category, treatment was started by giving Momordica fruit extract dose orally for 10 days and 15 days to two groups of rabbits, respectively. Then, livers of rabbits were damaged with acetaminophen and hepatoprotective effects of Momordica were observed.
Conclusion: The results showed that the animals treated with Momordica fruit extract experienced less liver damage due to acetaminophen intoxication, indicating that Momordica has hepatoprotective properties.

Key words: Liver function tests, Hepatocurative, Hepatoprotective, Momordica charantia, Acetaminophen.


 
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How to Cite this Article
Pubmed Style

Zahra K, Sohail MI, Malik MA. Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits. J Intercult Ethnopharmacol. 2012; 1(1): 7-12. doi:10.5455/jice.20120403013109



Web Style

Zahra K, Sohail MI, Malik MA. Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits. www.scopemed.org/?mno=16549 [Access: November 18, 2017]. doi:10.5455/jice.20120403013109



AMA (American Medical Association) Style

Zahra K, Sohail MI, Malik MA. Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits. J Intercult Ethnopharmacol. 2012; 1(1): 7-12. doi:10.5455/jice.20120403013109



Vancouver/ICMJE Style

Zahra K, Sohail MI, Malik MA. Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits. J Intercult Ethnopharmacol. (2012), [cited November 18, 2017]; 1(1): 7-12. doi:10.5455/jice.20120403013109



Harvard Style

Zahra, K., Sohail, M. I. & Malik, M. A. (2012) Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits. J Intercult Ethnopharmacol, 1 (1), 7-12. doi:10.5455/jice.20120403013109



Turabian Style

Zahra, Kanwal, Muhammad Imran Sohail, and Muhammad Anwar Malik. 2012. Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits. Journal of Intercultural Ethnopharmacology, 1 (1), 7-12. doi:10.5455/jice.20120403013109



Chicago Style

Zahra, Kanwal, Muhammad Imran Sohail, and Muhammad Anwar Malik. "Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits." Journal of Intercultural Ethnopharmacology 1 (2012), 7-12. doi:10.5455/jice.20120403013109



MLA (The Modern Language Association) Style

Zahra, Kanwal, Muhammad Imran Sohail, and Muhammad Anwar Malik. "Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits." Journal of Intercultural Ethnopharmacology 1.1 (2012), 7-12. Print. doi:10.5455/jice.20120403013109



APA (American Psychological Association) Style

Zahra, K., Sohail, M. I. & Malik, M. A. (2012) Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits. Journal of Intercultural Ethnopharmacology, 1 (1), 7-12. doi:10.5455/jice.20120403013109





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