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Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa

Bachir Benarba, Boumedienne Meddah.

Cited by (2)

Abstract
Aim: Aristolochia longa (from the family Aristolochiaceae) is widely used in Algerian traditional medicine. Here we document ethnomedicinal uses by local population of Mascara province (west Algeria) and we evaluate the antifungal activity, the phytochemical composition and total phenolic content of aqueous extract (decoction) of the roots of A. longa from Algeria. Material and Methods: The ethnobotanical investigation was carried out in Mascara Province (West Algeria). Antifungal activity was assessed against Saccharomyces cerevisiae. Total phenolic content was measured using the Folin-Ciocalteu’s reagent. Results: Our results showed that A. longa is widely used to treat several ailments such as cancer (38%), skin infections (14%) and diabetes (11%). Crushed roots are commonly used (89%) mixed with honey, milk, water or other medicinal plants. A. longa aqueous extract induced growth inhibition of S. cerevisiae cells in a dose- and time- dependent manner. An effective suppression of S. cerevisiae (97.06% inhibition of proliferation) was obtained at the 500µg/ml after 72h. Results of the phytochemical screening revealed that A. longa aqueous extract contained various bioactive compounds, including polyphenols and flavonoids. Total phenolic content in A. longa aqueous extract was found to be 6.07±0.12 mg (GAE)/g. Conclusion: A longa may be considered as a promising source of new drugs for treating cancer and as a good antifungal agent.

Key words: Aristolochia longa; ethnobotany; phytochemistry; antifungal; phenolic; Mascara; Algeria


 
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How to Cite this Article
Pubmed Style

Benarba B, Meddah B. Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa. J Intercult Ethnopharmacol. 2014; 3(4): 150-154. doi:10.5455/jice.20140826030222



Web Style

Benarba B, Meddah B. Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa. www.scopemed.org/?mno=166504 [Access: November 18, 2017]. doi:10.5455/jice.20140826030222



AMA (American Medical Association) Style

Benarba B, Meddah B. Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa. J Intercult Ethnopharmacol. 2014; 3(4): 150-154. doi:10.5455/jice.20140826030222



Vancouver/ICMJE Style

Benarba B, Meddah B. Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa. J Intercult Ethnopharmacol. (2014), [cited November 18, 2017]; 3(4): 150-154. doi:10.5455/jice.20140826030222



Harvard Style

Benarba, B. & Meddah, B. (2014) Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa. J Intercult Ethnopharmacol, 3 (4), 150-154. doi:10.5455/jice.20140826030222



Turabian Style

Benarba, Bachir, and Boumedienne Meddah. 2014. Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa. Journal of Intercultural Ethnopharmacology, 3 (4), 150-154. doi:10.5455/jice.20140826030222



Chicago Style

Benarba, Bachir, and Boumedienne Meddah. "Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa." Journal of Intercultural Ethnopharmacology 3 (2014), 150-154. doi:10.5455/jice.20140826030222



MLA (The Modern Language Association) Style

Benarba, Bachir, and Boumedienne Meddah. "Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa." Journal of Intercultural Ethnopharmacology 3.4 (2014), 150-154. Print. doi:10.5455/jice.20140826030222



APA (American Psychological Association) Style

Benarba, B. & Meddah, B. (2014) Ethnobotanical study, antifungal activity, phytochemical screening and total phenolic content of Algerian Aristolochia longa. Journal of Intercultural Ethnopharmacology, 3 (4), 150-154. doi:10.5455/jice.20140826030222





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