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Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.

Mohammad Shah Hafez Kabir, Mir Muhammad Nasir Uddin, S. M. Zahid Hosen.

Abstract
Background: Our study aims at exploring the hypoglycemic effect, efficacy and possible mode of action of ethanol extract of Alpinia nigra (EEAN) as an antidiabetic agent in animal model. Methods: Oral glucose tolerance test (OGTT) was used to identify primary hypoglycemic effect in mice. Three tests (glucose absorption, sucrose absorption and disaccharidase activity) were carried out by gut-perfusion and six segments studies to assess carbohydrate absorption and glucose utilization. Results: In OGTT, at 400 mg/kg and 800 mg/kg dose of EEAN extract significantly improved oral glucose tolerance among normal mice at 60 min and 90 min with compared to control. both doses of extract significantly (P

Key words: Alpinia nigra, OGTT, hypoglycemic effect, blood glucose, glucose tolerance


 
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How to Cite this Article
Pubmed Style

Kabir MSH, Uddin MMN, Hosen SMZ. Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.. J Intercult Ethnopharmacol. 2016; 5(2): 131-136. doi:10.5455/jice.20160307112256



Web Style

Kabir MSH, Uddin MMN, Hosen SMZ. Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.. www.scopemed.org/?mno=211572 [Access: November 18, 2017]. doi:10.5455/jice.20160307112256



AMA (American Medical Association) Style

Kabir MSH, Uddin MMN, Hosen SMZ. Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.. J Intercult Ethnopharmacol. 2016; 5(2): 131-136. doi:10.5455/jice.20160307112256



Vancouver/ICMJE Style

Kabir MSH, Uddin MMN, Hosen SMZ. Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.. J Intercult Ethnopharmacol. (2016), [cited November 18, 2017]; 5(2): 131-136. doi:10.5455/jice.20160307112256



Harvard Style

Kabir, M. S. H., Uddin, M. M. N. & Hosen, S. M. Z. (2016) Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.. J Intercult Ethnopharmacol, 5 (2), 131-136. doi:10.5455/jice.20160307112256



Turabian Style

Kabir, Mohammad Shah Hafez, Mir Muhammad Nasir Uddin, and S. M. Zahid Hosen. 2016. Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.. Journal of Intercultural Ethnopharmacology, 5 (2), 131-136. doi:10.5455/jice.20160307112256



Chicago Style

Kabir, Mohammad Shah Hafez, Mir Muhammad Nasir Uddin, and S. M. Zahid Hosen. "Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.." Journal of Intercultural Ethnopharmacology 5 (2016), 131-136. doi:10.5455/jice.20160307112256



MLA (The Modern Language Association) Style

Kabir, Mohammad Shah Hafez, Mir Muhammad Nasir Uddin, and S. M. Zahid Hosen. "Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.." Journal of Intercultural Ethnopharmacology 5.2 (2016), 131-136. Print. doi:10.5455/jice.20160307112256



APA (American Psychological Association) Style

Kabir, M. S. H., Uddin, M. M. N. & Hosen, S. M. Z. (2016) Investigation on hypoglycemic effects of ethanol extract of Alpinia nigra (Gaertn.) in animal model.. Journal of Intercultural Ethnopharmacology, 5 (2), 131-136. doi:10.5455/jice.20160307112256





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