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Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula

Adel Al-Marby, Chukwunonso ECC Ejike, Muhammad Jawad Nasim, Nasser A Awadh-Ali, Rwaida A Al-badani, Ghanem MA Alghamdi, Claus Jacob.

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Abstract
Aim/Background: The development of resistance to synthetic drugs by target organism is a major challenge facing medicine, yet locked within plants are phytochemicals used in herbal medicine (especially in the Arabian Peninsula) that may find application in this regard. In pursuit of unlocking these hidden treasures the methanol extracts of leaves, aerial parts, fruits and resins of seventeen plants used in the Arabian Peninsula were screened for antimicrobial activities. Methods: The nematicidal, antibacterial and antifungal activities using appropriate assays. Steinernema feltiae, Staphylococcus carnosus, Escherichia coli and Saccharomyces cerevisiae were used as test organisms. Concentrations of the extracts ranging from 0.5 to 20 mg/ml were tested and appropriate statistical tests performed on the data generated. Results: The results show that extracts from S. incanum, C. murale, C. myrrha, A. nobilis and A. biebersteinii were the most active, and had very high activities against two or more of the test organisms at low concentrations. Extracts of the leaves of S. incanum and resins of F. asafoetida were the most active nematicides, with significant activity at 0.5 mg/ml. Extracts of C. myrrha and C. murale had the most active antibacterial activity with inhibition zones of 12-15 mm and minimum inhibitory concentrations (MICs) of 2.5 mg/ml for both bacteria. Extracts of the leaves of A. biebersteinii were the most active fungicide, giving an MIC of 1.5 mg/ml. Conclusion: The results validate the use of these plants in ethnopharmacology, and open new vistas of opportunities for the development of cheap but effective agents that may be useful against infectious diseases.

Key words: antimicrobials, nematicides, medicinal plants, Solanum incanum, Commiphora myrrha, phytochemicals


 
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How to Cite this Article
Pubmed Style

Al-Marby A, Ejike CE, Nasim MJ, Awadh-Ali NA, Al-badani RA, Alghamdi GM, Jacob C. Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. J Intercult Ethnopharmacol. 2016; 5(2): 114-121. doi:10.5455/jice.20160217040157



Web Style

Al-Marby A, Ejike CE, Nasim MJ, Awadh-Ali NA, Al-badani RA, Alghamdi GM, Jacob C. Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. www.scopemed.org/?mno=214784 [Access: November 18, 2017]. doi:10.5455/jice.20160217040157



AMA (American Medical Association) Style

Al-Marby A, Ejike CE, Nasim MJ, Awadh-Ali NA, Al-badani RA, Alghamdi GM, Jacob C. Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. J Intercult Ethnopharmacol. 2016; 5(2): 114-121. doi:10.5455/jice.20160217040157



Vancouver/ICMJE Style

Al-Marby A, Ejike CE, Nasim MJ, Awadh-Ali NA, Al-badani RA, Alghamdi GM, Jacob C. Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. J Intercult Ethnopharmacol. (2016), [cited November 18, 2017]; 5(2): 114-121. doi:10.5455/jice.20160217040157



Harvard Style

Al-Marby, A., Ejike, C. E., Nasim, M. J., Awadh-Ali, N. A., Al-badani, R. A., Alghamdi, G. M. & Jacob, C. (2016) Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. J Intercult Ethnopharmacol, 5 (2), 114-121. doi:10.5455/jice.20160217040157



Turabian Style

Al-Marby, Adel, Chukwunonso ECC Ejike, Muhammad Jawad Nasim, Nasser A Awadh-Ali, Rwaida A Al-badani, Ghanem MA Alghamdi, and Claus Jacob. 2016. Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. Journal of Intercultural Ethnopharmacology, 5 (2), 114-121. doi:10.5455/jice.20160217040157



Chicago Style

Al-Marby, Adel, Chukwunonso ECC Ejike, Muhammad Jawad Nasim, Nasser A Awadh-Ali, Rwaida A Al-badani, Ghanem MA Alghamdi, and Claus Jacob. "Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula." Journal of Intercultural Ethnopharmacology 5 (2016), 114-121. doi:10.5455/jice.20160217040157



MLA (The Modern Language Association) Style

Al-Marby, Adel, Chukwunonso ECC Ejike, Muhammad Jawad Nasim, Nasser A Awadh-Ali, Rwaida A Al-badani, Ghanem MA Alghamdi, and Claus Jacob. "Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula." Journal of Intercultural Ethnopharmacology 5.2 (2016), 114-121. Print. doi:10.5455/jice.20160217040157



APA (American Psychological Association) Style

Al-Marby, A., Ejike, C. E., Nasim, M. J., Awadh-Ali, N. A., Al-badani, R. A., Alghamdi, G. M. & Jacob, C. (2016) Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. Journal of Intercultural Ethnopharmacology, 5 (2), 114-121. doi:10.5455/jice.20160217040157





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