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Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy

Luca Sorrentino, Salvatore Piraneo, Eliana Riggio, Silvia Basilicò, Alessandra Sartani, Daniela Bossi, Fabio Corsi.

Cited by (6)

Abstract
Aim: We administered A. montana 1000K to evaluate its benefits on post-operative blood loss and seroma production in women undergoing unilateral total mastectomy.
Methods: From 2012 to 2014, 53 women were randomly assigned to A. montana or placebo and were followed up to 5 days. The main endpoint was the reduction in blood and serum volumes collected in drainages. Secondary endpoints were duration of drainage, a self-evaluation of pain, and the presence of bruising or hematomas.
Results: The per-protocol analysis revealed a lower mean volume of blood and serum collected in drainages with A. montana (-94.40 mL; 95%CI 22.48-211.28; p=0.11). A regression model including treatment, volume collected in the drainage on the day of surgery and patient weight showed a statistically significant difference in favour of A. montana (-106.28 mL; 95%CI 9.45-203.11; p=0.03). Volumes collected on the day of surgery and following days were significantly lower with A. montana at day 2 (p=0.033) and 3 (p=0.0223). Secondary endpoints have not revealed significant differences.
Conclusions: A. montana 1000K could reduce post-operative blood and seroma collection in women undergoing unilateral total mastectomy. Larger studies are needed with different dilutions of A. montana to further validate these data.

Key words: Arnica montana, homeopathy, mastectomy, breast cancer, seroma


 
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This Article Cited By the following articles

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How to Cite this Article
Pubmed Style

Sorrentino L, Piraneo S, Riggio E, Basilicò S, Sartani A, Bossi D, Corsi F. Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy. J Intercult Ethnopharmacol. 2017; 6(1): 1-8. doi:10.5455/jice.20161229055245


Web Style

Sorrentino L, Piraneo S, Riggio E, Basilicò S, Sartani A, Bossi D, Corsi F. Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy. http://www.jicep.com/?mno=244972 [Access: January 23, 2018]. doi:10.5455/jice.20161229055245


AMA (American Medical Association) Style

Sorrentino L, Piraneo S, Riggio E, Basilicò S, Sartani A, Bossi D, Corsi F. Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy. J Intercult Ethnopharmacol. 2017; 6(1): 1-8. doi:10.5455/jice.20161229055245



Vancouver/ICMJE Style

Sorrentino L, Piraneo S, Riggio E, Basilicò S, Sartani A, Bossi D, Corsi F. Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy. J Intercult Ethnopharmacol. (2017), [cited January 23, 2018]; 6(1): 1-8. doi:10.5455/jice.20161229055245



Harvard Style

Sorrentino, L., Piraneo, S., Riggio, E., Basilicò, S., Sartani, A., Bossi, D. & Corsi, F. (2017) Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy. J Intercult Ethnopharmacol, 6 (1), 1-8. doi:10.5455/jice.20161229055245



Turabian Style

Sorrentino, Luca, Salvatore Piraneo, Eliana Riggio, Silvia Basilicò, Alessandra Sartani, Daniela Bossi, and Fabio Corsi. 2017. Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy. Journal of Intercultural Ethnopharmacology, 6 (1), 1-8. doi:10.5455/jice.20161229055245



Chicago Style

Sorrentino, Luca, Salvatore Piraneo, Eliana Riggio, Silvia Basilicò, Alessandra Sartani, Daniela Bossi, and Fabio Corsi. "Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy." Journal of Intercultural Ethnopharmacology 6 (2017), 1-8. doi:10.5455/jice.20161229055245



MLA (The Modern Language Association) Style

Sorrentino, Luca, Salvatore Piraneo, Eliana Riggio, Silvia Basilicò, Alessandra Sartani, Daniela Bossi, and Fabio Corsi. "Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy." Journal of Intercultural Ethnopharmacology 6.1 (2017), 1-8. Print. doi:10.5455/jice.20161229055245



APA (American Psychological Association) Style

Sorrentino, L., Piraneo, S., Riggio, E., Basilicò, S., Sartani, A., Bossi, D. & Corsi, F. (2017) Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy. Journal of Intercultural Ethnopharmacology, 6 (1), 1-8. doi:10.5455/jice.20161229055245





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