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Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.

Alessandro Venditti, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, Armandodoriano Bianco.

Abstract
In this paper is reported an in deep study of the glycosidic fraction of S. alopecuros subsp. divulsa which permitted to widen the knowledge on its iridoid pattern, being constituted also by ajugoside (1), reptoside (6) and 6-O-acetyl-ajugol (7), besides 8-O-acetylharpagide (2), harpagide (3), allobetonicoside (4), 4′-O-galactopyranosyl-teuhircoside (5) which had been already isolated from this species. The phenolic compounds isolated during the study resulted to be chlorogenic acid (8), β-arbutin (9), verbascoside (10) and stachysoside A (11) instead. Except for the reconfirmed verbascoside (10), the other phenolic compounds were recognized for the first time in the studied species. The complete NMR assignment of compound (1) by means of bidimensional techniques is reported and both the chemotaxonomic and pharmacologic relevance of the isolated compounds are discussed.

Key words: Iridoid, Chemotaxonomy, NMR, Chlorogenic acid, β-arbutin, Phenylethanoid glycosides.


 
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Pubmed Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Intercult Ethnopharmacol. 2017; 6(2): 144-153. doi:10.5455/jice.20170327073801



Web Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. www.scopemed.org/?mno=248220 [Access: October 17, 2017]. doi:10.5455/jice.20170327073801



AMA (American Medical Association) Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Intercult Ethnopharmacol. 2017; 6(2): 144-153. doi:10.5455/jice.20170327073801



Vancouver/ICMJE Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Intercult Ethnopharmacol. (2017), [cited October 17, 2017]; 6(2): 144-153. doi:10.5455/jice.20170327073801



Harvard Style

Venditti, A., Frezza, C., Lorenzetti, L. M., Maggi, F., Serafini, M. & Bianco, A. (2017) Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Intercult Ethnopharmacol, 6 (2), 144-153. doi:10.5455/jice.20170327073801



Turabian Style

Venditti, Alessandro, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, and Armandodoriano Bianco. 2017. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. Journal of Intercultural Ethnopharmacology, 6 (2), 144-153. doi:10.5455/jice.20170327073801



Chicago Style

Venditti, Alessandro, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, and Armandodoriano Bianco. "Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.." Journal of Intercultural Ethnopharmacology 6 (2017), 144-153. doi:10.5455/jice.20170327073801



MLA (The Modern Language Association) Style

Venditti, Alessandro, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, and Armandodoriano Bianco. "Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.." Journal of Intercultural Ethnopharmacology 6.2 (2017), 144-153. Print. doi:10.5455/jice.20170327073801



APA (American Psychological Association) Style

Venditti, A., Frezza, C., Lorenzetti, L. M., Maggi, F., Serafini, M. & Bianco, A. (2017) Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. Journal of Intercultural Ethnopharmacology, 6 (2), 144-153. doi:10.5455/jice.20170327073801





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