eJManager
 
E-ISSN 2146-8397
 

Original Research Open Access


Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.

Alessandro Venditti, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, Armandodoriano Bianco.

Cited by (1)

Abstract
In this paper is reported an in deep study of the glycosidic fraction of S. alopecuros subsp. divulsa which permitted to widen the knowledge on its iridoid pattern, being constituted also by ajugoside (1), reptoside (6) and 6-O-acetyl-ajugol (7), besides 8-O-acetylharpagide (2), harpagide (3), allobetonicoside (4), 4′-O-galactopyranosyl-teuhircoside (5) which had been already isolated from this species. The phenolic compounds isolated during the study resulted to be chlorogenic acid (8), β-arbutin (9), verbascoside (10) and stachysoside A (11) instead. Except for the reconfirmed verbascoside (10), the other phenolic compounds were recognized for the first time in the studied species. The complete NMR assignment of compound (1) by means of bidimensional techniques is reported and both the chemotaxonomic and pharmacologic relevance of the isolated compounds are discussed.

Key words: Iridoid, Chemotaxonomy, NMR, Chlorogenic acid, β-arbutin, Phenylethanoid glycosides.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Alessandro Venditti
Articles by Claudio Frezza
Articles by Lorenzo M. Lorenzetti
Articles by Filippo Maggi
Articles by Mauro Serafini
Articles by Armandodoriano Bianco
on Google
on Google Scholar
Article Statistics
 Viewed: 1797
Downloaded: 531
Cited: 1

This Article Cited By the following articles

Iridoid glycosides and polyphenolic compounds from Teucrium chamaedrys L.
Natural Product Research 2017; (): 1.

1
 

How to Cite this Article
Pubmed Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2017; 6(2): 144-153. doi:10.5455/jice.20170327073801


Web Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. http://www.jicep.com/?mno=248220 [Access: February 20, 2018]. doi:10.5455/jice.20170327073801


AMA (American Medical Association) Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2017; 6(2): 144-153. doi:10.5455/jice.20170327073801



Vancouver/ICMJE Style

Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Complement Med Res (Formerly J Intercult Ethnopharmacol). (2017), [cited February 20, 2018]; 6(2): 144-153. doi:10.5455/jice.20170327073801



Harvard Style

Venditti, A., Frezza, C., Lorenzetti, L. M., Maggi, F., Serafini, M. & Bianco, A. (2017) Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. J Complement Med Res (Formerly J Intercult Ethnopharmacol), 6 (2), 144-153. doi:10.5455/jice.20170327073801



Turabian Style

Venditti, Alessandro, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, and Armandodoriano Bianco. 2017. Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. Journal of Complementary Medicine Research (Formerly known as Journal of Intercultural Ethnopharmacology (2012-2017)), 6 (2), 144-153. doi:10.5455/jice.20170327073801



Chicago Style

Venditti, Alessandro, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, and Armandodoriano Bianco. "Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.." Journal of Complementary Medicine Research (Formerly known as Journal of Intercultural Ethnopharmacology (2012-2017)) 6 (2017), 144-153. doi:10.5455/jice.20170327073801



MLA (The Modern Language Association) Style

Venditti, Alessandro, Claudio Frezza, Lorenzo M. Lorenzetti, Filippo Maggi, Mauro Serafini, and Armandodoriano Bianco. "Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.." Journal of Complementary Medicine Research (Formerly known as Journal of Intercultural Ethnopharmacology (2012-2017)) 6.2 (2017), 144-153. Print. doi:10.5455/jice.20170327073801



APA (American Psychological Association) Style

Venditti, A., Frezza, C., Lorenzetti, L. M., Maggi, F., Serafini, M. & Bianco, A. (2017) Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park and its potential pharmacologic uses.. Journal of Complementary Medicine Research (Formerly known as Journal of Intercultural Ethnopharmacology (2012-2017)), 6 (2), 144-153. doi:10.5455/jice.20170327073801





Most Viewed Articles
  • Role of Cyperus rotundus oil in decreasing hair growth
    GHADA FAROUK ABD EL-KAREAM
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(2): 111-118
    » Abstract & References » doi: 10.5455/jice.20120626100304

  • Ethno-dentistry: popular medicinal plants used for dental diseases in India
    Amit Bhardwaj, Shalu Verma Bhardwaj
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 62-65
    » Abstract & References » doi: 10.5455/jice.20120322035152

  • Studies with Myrtus communis L.: Anticancer Properties
    Recai Ogur
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2014; 3(4): 135-137
    » Abstract & References » doi: 10.5455/jice.20140803044831

  • Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium
    Rajeev Singh, Pawan Kumar Verma, Gagandeep Singh
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(2): 101-104
    » Abstract & References » doi: 10.5455/jice.20120525014326

  • Antimicrobial and phytochemical evaluation of the leaf, stem bark and root extracts of Cyathula prostrata (L) Blume against some human pathogens
    Gideon Ikechukwu Ogu, Williams Omotola Tanimowo, Perpetua Ugonna Nwachukwu, Bright Esegbuyota Igere
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 35-43
    » Abstract & References » doi: 10.5455/jice.20120407085952

  • Herbal Antibacterials: A Review
    Chirag Modi, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, Madhavi Awale
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 52-61
    » Abstract & References » doi: 10.5455/jice.20120207113423

  • Preliminary phytochemical screening and evaluation of antibacterial activity of Dichrocepala integrifolia (L.f) O. kuntze
    Tesfaye Mohammed, Chalachew Teshale
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 30-34
    » Abstract & References » doi: 10.5455/jice.20120401054654

  • Medicinal plants with potential anti-arthritic activity:
    Manjusha Choudhary, Vipin Kumar, Hitesh Malhotra, Surender Singh
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2015; 4(2): 147-179
    » Abstract & References » doi: 10.5455/jice.20150313021918

  • Phytochemical and antibacterial activity of the extracts of Fagara zanthoxyloides on selected cariogenic and enteric bacterial isolates
    Martins Ajibade Adefisoye, Kwashie AjibadeAko-Nai, Mary Adejumoke Bisi-Johnson
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 1-6
    » Abstract & References » doi: 10.5455/jice.55-1333123486

  • Effect of Momordica charantia (bitter melon) on serum glucose level and various protein parameters in acetaminophen intoxicated rabbits
    Kanwal Zahra, Muhammad Imran Sohail, Muhammad Anwar Malik
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 7-12
    » Abstract & References » doi: 10.5455/jice.20120403013109

  • Most Downloaded
  • Studies with Myrtus communis L.: Anticancer Properties
    Recai Ogur
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2014; 3(4): 135-137
    » Abstract & References » doi: 10.5455/jice.20140803044831

  • Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium
    Rajeev Singh, Pawan Kumar Verma, Gagandeep Singh
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(2): 101-104
    » Abstract & References » doi: 10.5455/jice.20120525014326

  • Herbal Antibacterials: A Review
    Chirag Modi, Shailesh Mody, Hitesh Patel, Ghanshyam Dudhatra, Avinash Kumar, Madhavi Awale
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 52-61
    » Abstract & References » doi: 10.5455/jice.20120207113423

  • Ethno-dentistry: popular medicinal plants used for dental diseases in India
    Amit Bhardwaj, Shalu Verma Bhardwaj
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 62-65
    » Abstract & References » doi: 10.5455/jice.20120322035152

  • Antimicrobial and phytochemical evaluation of the leaf, stem bark and root extracts of Cyathula prostrata (L) Blume against some human pathogens
    Gideon Ikechukwu Ogu, Williams Omotola Tanimowo, Perpetua Ugonna Nwachukwu, Bright Esegbuyota Igere
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 35-43
    » Abstract & References » doi: 10.5455/jice.20120407085952

  • Role of Cyperus rotundus oil in decreasing hair growth
    GHADA FAROUK ABD EL-KAREAM
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(2): 111-118
    » Abstract & References » doi: 10.5455/jice.20120626100304

  • A review on ethnopharmacological potential of Aloe vera L.
    Md. Shamim Hossain, A.N.M Mamun-Or-Rashid, Nayeem Md. Towfique, Monokesh Kumer Sen
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2013; 2(2): 113-120
    » Abstract & References » doi: 10.5455/jice.20130612035300

  • Use of Aqueous Extract of Corn Silk in the Treatment of Urinary Tract Infection
    Ahmed Salih Sahib, Imad Hashim Mohammed, Saba Jasim Hamdan
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(2): 93-96
    » Abstract & References » doi: 10.5455/jice.20120525123150

  • Preliminary phytochemical screening and evaluation of antibacterial activity of Dichrocepala integrifolia (L.f) O. kuntze
    Tesfaye Mohammed, Chalachew Teshale
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 30-34
    » Abstract & References » doi: 10.5455/jice.20120401054654

  • Phytochemical and antibacterial activity of the extracts of Fagara zanthoxyloides on selected cariogenic and enteric bacterial isolates
    Martins Ajibade Adefisoye, Kwashie AjibadeAko-Nai, Mary Adejumoke Bisi-Johnson
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 1-6
    » Abstract & References » doi: 10.5455/jice.55-1333123486

  • Most Cited Articles
  • Total phenolic, flavonoids and tannin contents in different extracts of Artemisia absinthium
    Rajeev Singh, Pawan Kumar Verma, Gagandeep Singh
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(2): 101-104
    » Abstract & References » doi: 10.5455/jice.20120525014326
    Cited : 28 times [Click to see citing articles]

  • Antimicrobial and phytochemical evaluation of the leaf, stem bark and root extracts of Cyathula prostrata (L) Blume against some human pathogens
    Gideon Ikechukwu Ogu, Williams Omotola Tanimowo, Perpetua Ugonna Nwachukwu, Bright Esegbuyota Igere
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 35-43
    » Abstract & References » doi: 10.5455/jice.20120407085952
    Cited : 11 times [Click to see citing articles]

  • Some pharmacological effects of cinnamon and ginger herbs in obese diabetic rats
    Mostafa Abbas Shalaby, Hamed Yahya Saifan
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2014; 3(4): 144-149
    » Abstract & References » doi: 10.5455/jice.20140818050741
    Cited : 11 times [Click to see citing articles]

  • Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro
    Emmanuel Anyachukwu Irondi, Samson Olalekan Agboola, Ganiyu Oboh, Aline Augusti Boligon, Margareth Linde Athayde, Francis O. Shode
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2016; 5(2): 122-130
    » Abstract & References » doi: 10.5455/jice.20160321115402
    Cited : 11 times [Click to see citing articles]

  • Analgesic, Anti-inflammatory and Antihyperlipidemic Activities of Commiphora molmol Extract (Myrrh)
    Mostafa Abbas Shalaby, Ashraf Abd-Elkhalik Hammouda
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2014; 3(2): 56-62
    » Abstract & References » doi: 10.5455/jice.20140130015014
    Cited : 9 times [Click to see citing articles]

  • Potential antimalarials from African natural products: a review
    Bashir Lawal, Oluwatosin Kudirat Shittu, Adamu Yusuf Kabiru, Ali Audu Jigam, Maimuna Bello Umar, Eustace Bonghan Berinyuy, Blessing Uchenna Alozieuwa
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2015; 4(4): 318-343
    » Abstract & References » doi: 10.5455/jice.20150928102856
    Cited : 8 times [Click to see citing articles]

  • Herbal medicine use among Turkish patients with chronic diseases
    Mnevver Tulunay, Cenk Aypak, Hlya Yklkan, Sleyman Grpeliolu
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2015; 4(3): 217-220
    » Abstract & References » doi: 10.5455/jice.20150623090040
    Cited : 7 times [Click to see citing articles]

  • Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce postoperative seroma and bleeding in patients undergoing total mastectomy
    Luca Sorrentino, Salvatore Piraneo, Eliana Riggio, Silvia Basilic, Alessandra Sartani, Daniela Bossi, Fabio Corsi
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2017; 6(1): 1-8
    » Abstract » doi: 10.5455/jice.20161229055245
    Cited : 6 times [Click to see citing articles]

  • Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants
    Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 19-24
    » Abstract & References » doi: 10.5455/jice.20120227104636
    Cited : 5 times [Click to see citing articles]

  • Preliminary phytochemical screening and evaluation of antibacterial activity of Dichrocepala integrifolia (L.f) O. kuntze
    Tesfaye Mohammed, Chalachew Teshale
    J Complement Med Res (Formerly J Intercult Ethnopharmacol). 2012; 1(1): 30-34
    » Abstract & References » doi: 10.5455/jice.20120401054654
    Cited : 5 times [Click to see citing articles]