E-ISSN 2577-5669
 

Review Article 


The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis

Samira Jamali*, Elnaz Mousavi, Sepideh Behzadi, Golchin Jabbari, Ali Eslambol Nassaj, Ayşe Karadayi.

Abstract
Objective: The results detailed that a few systemic disorders may impact endodontic healing results. A systematic review can complete such analyses to investigate endodontic infection and cardiovascular disease thoroughly. This systematic review and meta-analysis aimed to evaluate the effect of Endodontic Infections on Cardiovascular Disease.
Method: Our search strategy was to screen the relevant articles on the electronic databases of Google Scholar, MEDLINE, Cochrane Library, PubMed, ISI, and Embase, published from January 2005 to January 2020. The management of electronic titles was performed using Endnote X9 software. The main keywords for the search process included "Cardiovascular disease OR CVD", "LEO"," Endodontics", "Endodontic Infections" "dental evaluations", "missing teeth", "apical lesions", "bone loss". The current systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Results: Electronic and manual searches resulted in 53 relevant titles and abstracts. Eventually, five publications were eligible for the inclusion criteria required for this systematic review. The risk ratio (RR) was 1, and the 95% certainty interval (CI) was 3.56–15.87; the obtained very low certainty indicated that the lesion of endodontic origin (LEO) might impact Cardiovascular disease (CVD) improvement.
Conclusion: Endodontic Infection may or may not exert a few effects on the systemic Cardiovascular disease (CVD), and there was a low level of proof.

Key words: Endodontic infection, Cardiovascular disease, CVD, LEO, pathogenesis.


 
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How to Cite this Article
Pubmed Style

Jamali S, Mousavi E, Behzadi S, Jabbari G, Nassaj AE, Karadayi A. The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis. J Complement Med Res. 2022; 13(3): 105-108. doi:10.5455/jcmr.2022.13.03.23


Web Style

Jamali S, Mousavi E, Behzadi S, Jabbari G, Nassaj AE, Karadayi A. The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis. https://www.jocmr.com/?mno=105478 [Access: November 03, 2022]. doi:10.5455/jcmr.2022.13.03.23


AMA (American Medical Association) Style

Jamali S, Mousavi E, Behzadi S, Jabbari G, Nassaj AE, Karadayi A. The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis. J Complement Med Res. 2022; 13(3): 105-108. doi:10.5455/jcmr.2022.13.03.23



Vancouver/ICMJE Style

Jamali S, Mousavi E, Behzadi S, Jabbari G, Nassaj AE, Karadayi A. The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis. J Complement Med Res. (2022), [cited November 03, 2022]; 13(3): 105-108. doi:10.5455/jcmr.2022.13.03.23



Harvard Style

Jamali, S., Mousavi, . E., Behzadi, . S., Jabbari, . G., Nassaj, . A. E. & Karadayi, . A. (2022) The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis. J Complement Med Res, 13 (3), 105-108. doi:10.5455/jcmr.2022.13.03.23



Turabian Style

Jamali, Samira, Elnaz Mousavi, Sepideh Behzadi, Golchin Jabbari, Ali Eslambol Nassaj, and Ayşe Karadayi. 2022. The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis. Journal of Complementary Medicine Research, 13 (3), 105-108. doi:10.5455/jcmr.2022.13.03.23



Chicago Style

Jamali, Samira, Elnaz Mousavi, Sepideh Behzadi, Golchin Jabbari, Ali Eslambol Nassaj, and Ayşe Karadayi. "The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis." Journal of Complementary Medicine Research 13 (2022), 105-108. doi:10.5455/jcmr.2022.13.03.23



MLA (The Modern Language Association) Style

Jamali, Samira, Elnaz Mousavi, Sepideh Behzadi, Golchin Jabbari, Ali Eslambol Nassaj, and Ayşe Karadayi. "The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis." Journal of Complementary Medicine Research 13.3 (2022), 105-108. Print. doi:10.5455/jcmr.2022.13.03.23



APA (American Psychological Association) Style

Jamali, S., Mousavi, . E., Behzadi, . S., Jabbari, . G., Nassaj, . A. E. & Karadayi, . A. (2022) The Effect of Endodontic Infection on the Pathogenesis of the Systematic Disease: A Systematic Review and Meta-analysis. Journal of Complementary Medicine Research, 13 (3), 105-108. doi:10.5455/jcmr.2022.13.03.23