E-ISSN 2577-5669
 

Original Research 


Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract

Prathiba Reichal, *S Rajeshkumar, T Lakshmi, Anitha Roy.

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  • Abstract
    Introduction: Coffee bean powder has a rich source of natural antioxidant and anti-inflammatory properties due to the
    presence of chlorogenic and phenolic acid components. The chlorogenic and phenolic acids along with other aromatic
    compounds are presented to have antibacterial effects against pathogenic microorganisms thereby preventing the invasion
    of dental caries over the tooth surface. The anticariogenic agents in coffee bean powder were found to be effective
    against s.mutans and e.faecalis. Inflammation is well understood as a critical biological response protecting the host’s
    body from pathogens to maintain tissue homeostasis. Hence, the current study aims to evaluate the anticariogenic and
    anti-inflammatory activity of coffee bean powder ethanolic extract.
    Materials and Methods: 40 mg of coffee bean powder was diluted in 25ml of ethanolic solution and was boiled for 20
    minutes to produce 20 ml of coffee bean powder ethanolic extract. Anticariogenic activity was carried against the strains
    of s.mutans, e.faecalis, s.aureus and c.albicans by disc diffusion method in MHA agar and the zone of inhibition was
    determined. Anti-inflammatory activity was achieved by using Muzushima and Kabayashi method of test with specific
    alteration and the reagent was bovine serum albumin with diclofenac sodium as standard.
    Results and discussion: The zone of inhibition of s.mutans in 100µL of coffee bean powder ethanolic extract was 14mm.
    The zone of inhibition of c.albicans in 100µLwas 13mm which is higher than the standard antibody. The effectiveness
    inhibition of bacteria is found to increase with increase in the concentration of the extract. Similarly, anti-inflammatory
    activity observed a value of 84.8% in 50µL concentration which is higher than the standard diclofenac sodium compound.
    Conclusion: Hence the current study concludes that coffee bean powder ethanolic extract can be used as a potent anti-cariogenic and anti-inflammatory agent against dental caries and tissue injuries

    Key words: Anticariogenic activity Green chemical, Innovative synthesis,Nanoparticles


     
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    How to Cite this Article
    Pubmed Style

    Reichal P, Rajeshkumar S, Lakshmi T, Roy A. Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract. J Complement Med Res. 2022; 13(3): 19-23. doi:10.5455/jcmr.2022.13.03.04


    Web Style

    Reichal P, Rajeshkumar S, Lakshmi T, Roy A. Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract. https://www.jocmr.com/?mno=57255 [Access: March 21, 2023]. doi:10.5455/jcmr.2022.13.03.04


    AMA (American Medical Association) Style

    Reichal P, Rajeshkumar S, Lakshmi T, Roy A. Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract. J Complement Med Res. 2022; 13(3): 19-23. doi:10.5455/jcmr.2022.13.03.04



    Vancouver/ICMJE Style

    Reichal P, Rajeshkumar S, Lakshmi T, Roy A. Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract. J Complement Med Res. (2022), [cited March 21, 2023]; 13(3): 19-23. doi:10.5455/jcmr.2022.13.03.04



    Harvard Style

    Reichal, P., Rajeshkumar, . S., Lakshmi, . T. & Roy, . A. (2022) Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract. J Complement Med Res, 13 (3), 19-23. doi:10.5455/jcmr.2022.13.03.04



    Turabian Style

    Reichal, Prathiba, S Rajeshkumar, T Lakshmi, and Anitha Roy. 2022. Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract. Journal of Complementary Medicine Research, 13 (3), 19-23. doi:10.5455/jcmr.2022.13.03.04



    Chicago Style

    Reichal, Prathiba, S Rajeshkumar, T Lakshmi, and Anitha Roy. "Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract." Journal of Complementary Medicine Research 13 (2022), 19-23. doi:10.5455/jcmr.2022.13.03.04



    MLA (The Modern Language Association) Style

    Reichal, Prathiba, S Rajeshkumar, T Lakshmi, and Anitha Roy. "Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract." Journal of Complementary Medicine Research 13.3 (2022), 19-23. Print. doi:10.5455/jcmr.2022.13.03.04



    APA (American Psychological Association) Style

    Reichal, P., Rajeshkumar, . S., Lakshmi, . T. & Roy, . A. (2022) Anticariogenic and Anti-Inflammatory Activity of Coffee Bean Powder Ethanolic Extract. Journal of Complementary Medicine Research, 13 (3), 19-23. doi:10.5455/jcmr.2022.13.03.04