E-ISSN 2577-5669
 

Research Article 


Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI.

Abstract
Introduction: Mortality rates of coronavirus disease increased across the world, most patients who hospitalized with covid-19 had good prognosis while a few died. In this study we are going to show that if the Laboratory abnormalities of Renal, Hepatic, Inflammation, Biochemical, Cell blood count, VBG, Cardiac, and Coagulation, before the beginning of drug treatment is death risk factors for COVID-19 patients.
Method: This retrospective cohort study performed on 845 Covid-19 patients, hospitalized in Imam Hossein hospital, Tehran, Iran. Demographic & laboratory were collected by Continuous sampling method from HIS. For data analysis, SPSS 26 software and Chi-square, Fisher's exact, univariable & multivariable logistic regression were used.
Result: Total hospitalized patients were 845 (643 alive, and 202 death). Logistic regression showed that laboratory data such as renal enzyme, Na, Ca, Coagulation, Cell Blood Count , VBG & cardiac enzyme such as CPK, and Troponin were associated with death, while hepatic; Ck-mb, LDH, ESR, CRP, Mg, K, and platelet were not associated.
Conclusion: In this study we found that increased of the level of WBC, BUN, Cr, Na, PT, INR, CPK, & Troponin and decreased of lymphocyte level on admission were associated with increased risk of mortality due to COVID‐19 infection and these are most important predictors of mortality in hospitalized COVID‐19 patients.

Key words: Laboratory abnormalities, radiologic, mortality, covid-19


 
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How to Cite this Article
Pubmed Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI. Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19. J Complement Med Res. 2021; 12(4): 92-97. doi:10.5455/jcmr.2021.12.04.14


Web Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI. Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19. https://www.jocmr.com/?mno=36095 [Access: August 07, 2022]. doi:10.5455/jcmr.2021.12.04.14


AMA (American Medical Association) Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI. Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19. J Complement Med Res. 2021; 12(4): 92-97. doi:10.5455/jcmr.2021.12.04.14



Vancouver/ICMJE Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI. Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19. J Complement Med Res. (2021), [cited August 07, 2022]; 12(4): 92-97. doi:10.5455/jcmr.2021.12.04.14



Harvard Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI (2021) Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19. J Complement Med Res, 12 (4), 92-97. doi:10.5455/jcmr.2021.12.04.14



Turabian Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI. 2021. Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19. Journal of Complementary Medicine Research, 12 (4), 92-97. doi:10.5455/jcmr.2021.12.04.14



Chicago Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI. "Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19." Journal of Complementary Medicine Research 12 (2021), 92-97. doi:10.5455/jcmr.2021.12.04.14



MLA (The Modern Language Association) Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI. "Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19." Journal of Complementary Medicine Research 12.4 (2021), 92-97. Print. doi:10.5455/jcmr.2021.12.04.14



APA (American Psychological Association) Style

SARA GHASEMINEJAD, MARYAM AHMADI CHEGINI, ESMAEIL SARIKHANI-KHORRAMI, MAHDI FARDI, ESHAGH RAMEZANI, ALI KALVANDI, SAMIEH MORADKHANI (2021) Association Of Laboratory Abnormalities Before the Beginning of Drug Treatment with Mortality of Hospitalized Patients with Covid-19. Journal of Complementary Medicine Research, 12 (4), 92-97. doi:10.5455/jcmr.2021.12.04.14